When you think of comfort food that feels like a warm hug, Stuffed Meatloaf with Mozzarella tops the list. It’s a classic dish with a delicious twist—tender, juicy ground meat wrapped around a luscious, gooey mozzarella core that melts with every slice. This dish takes the homestyle meatloaf we all know and love and elevates it with Italian-inspired flavors, aromatic herbs, and that irresistible cheese pull that makes every bite extra satisfying. It’s hearty enough for Sunday family dinners yet easy enough for a weeknight meal. Whether you’re hosting guests or simply craving something warm and fulfilling, this stuffed meatloaf promises to impress every time.

Full Recipe

Ingredients

• 800 g (1.7 lbs) ground beef or a beef-pork mix

• 1 onion, finely chopped

• 2 cloves garlic, minced

• 2 eggs

• 80 g (¾ cup) breadcrumbs

• 3 tbsp milk

• 2 tbsp ketchup or tomato paste

• 1 tbsp Worcestershire sauce

• 1 tsp salt

• ½ tsp black pepper

• 1 tsp dried oregano

• ½ tsp dried thyme

• ½ tsp paprika

• 200 g (7 oz) mozzarella cheese, sliced or shredded

• 1 tbsp olive oil (for greasing)

• Optional glaze: 2 tbsp ketchup mixed with 1 tbsp brown sugar and 1 tsp mustard

Cooking Directions

1. Prepare the Oven: Preheat your oven to 180°C (350°F) and grease a loaf pan or line it with parchment paper for easy cleanup.

2. Mix the Meatloaf Base: In a large bowl, combine the ground beef, chopped onion, minced garlic, eggs, breadcrumbs, milk, ketchup, Worcestershire sauce, salt, pepper, oregano, thyme, and paprika. Mix well but don’t overwork the meat; you want it tender, not tough.

3. Shape and Fill: Divide the mixture into two portions. Press one half into the loaf pan and create a shallow indentation down the center. This will hold your cheese filling.

4. Add the Mozzarella: Layer mozzarella slices or shredded cheese into the groove, ensuring even distribution. Leave a bit of space at the edges to prevent the cheese from leaking out during baking.

5. Seal and Shape: Add the remaining meat mixture on top and press it gently to seal the cheese inside. Smooth the top and shape it evenly.

6. Add Glaze (Optional): Spread the ketchup glaze evenly over the top for a sweet and tangy finish.

7. Bake: Place in the oven and bake for about 50–60 minutes, or until fully cooked through and golden on top.

8. Rest Before Serving: Allow the meatloaf to rest for at least 10 minutes before slicing. This step ensures that the juices redistribute evenly and the cheese stays inside.

9. Serve: Slice and serve warm, letting that molten mozzarella center steal the show.

Nutrients

• Calories: ~420 kcal per serving

• Protein: 28 g

• Fat: 28 g

• Carbohydrates: 8 g

• Fiber: 1 g

• Calcium: 180 mg

• Iron: 15% of daily value

• Sodium: 780 mg

Why You’ll Love This Recipe

This Stuffed Meatloaf with Mozzarella is everything comfort food should be—rich, flavorful, and loaded with that cozy homemade charm. It transforms a familiar, humble classic into a dinner that feels restaurant-worthy, yet it’s simple enough to make on a busy night. The cheesy center keeps every slice moist and satisfying, while the herby meat mixture delivers a balanced flavor profile. Plus, it’s versatile! You can play around with different fillings, sauces, or glazes depending on what’s in your fridge. It’s perfect for family gatherings, potlucks, or any night when you want to put something truly special on the table without a lot of fuss.

The Origins and Inspiration Behind the Dish

The concept of meatloaf dates back centuries, with variations found across Europe long before it became a staple in American kitchens. Originally, meatloaf was a practical way to stretch ingredients—mixing ground meat with breadcrumbs and spices to make a hearty, economical meal. When it made its way to the United States, it evolved into the beloved comfort food we know today. The stuffed version, however, takes cues from Italian cuisine, particularly polpettone ripieno, which often includes cheese or vegetables rolled inside a flavorful meat mixture. Combining the traditional American meatloaf technique with the indulgent Italian flair of melted mozzarella creates the perfect fusion of nostalgia and innovation.

Ingredient Spotlight

Ground Beef: The foundation of the dish. Choose a mix with about 15–20% fat for the juiciest result. Too lean, and the loaf will dry out.
Mozzarella Cheese: Melts beautifully, creating that irresistible gooey center. Fresh mozzarella gives a creamier texture, while shredded mozzarella offers even distribution.
Breadcrumbs: They hold everything together while keeping the texture light. You can use panko for extra fluffiness or whole-wheat crumbs for a healthier twist.
Eggs: They act as a binder and help the meatloaf stay firm but tender.
Worcestershire Sauce & Tomato Paste: These deepen the flavor, giving a rich umami and tangy base that keeps the meatloaf from tasting bland.
Herbs and Spices: Oregano, thyme, and paprika infuse the dish with warmth and a subtle Mediterranean note that pairs perfectly with the cheese filling.

Storage and Reheating Tips

Got leftovers? Lucky you. Store cooled meatloaf slices in an airtight container in the refrigerator for up to 4 days. For longer storage, wrap slices in foil and freeze for up to 2 months. To reheat, thaw overnight (if frozen), then warm in a 160°C (320°F) oven for 10–15 minutes or microwave gently until heated through. If you want to keep it juicy, drizzle a bit of broth or tomato sauce before reheating.

Common Variations to Try

Italian Style: Add chopped sun-dried tomatoes, spinach, or basil inside with the mozzarella.
BBQ Twist: Swap the glaze for smoky barbecue sauce for a tangy, caramelized finish.
Mediterranean: Mix in crumbled feta, olives, and roasted red peppers instead of mozzarella for a different flavor profile.
Double Cheese Version: Layer cheddar or provolone along with mozzarella for a richer, cheesier surprise.
Vegetable Boost: Grate carrots or zucchini into the meat mixture for added moisture and nutrition.

Pairing Recommendations

Serve your stuffed meatloaf with a side of creamy mashed potatoes, garlic-roasted vegetables, or buttered green beans. If you want something lighter, go for a crisp green salad with balsamic vinaigrette to cut through the richness of the cheese. For bread lovers, warm garlic bread or crusty baguette slices make the perfect companion. Beverage-wise, red wines like Merlot, Chianti, or Cabernet Sauvignon pair beautifully with the meaty depth, while sparkling water with lemon or iced tea offers a refreshing, non-alcoholic option.

Health Benefits

Despite being indulgent, this dish offers a surprising number of nutrients. The protein from the beef supports muscle repair and energy, while mozzarella provides a good dose of calcium for healthy bones. The eggs add extra protein and nutrients like vitamin B12, while the herbs contribute antioxidants and anti-inflammatory properties. Using baked preparation instead of frying helps keep it lighter on the fat side, and by incorporating vegetables or whole-grain breadcrumbs, you can easily make it even more wholesome.

Conclusion

In every sense, Stuffed Meatloaf with Mozzarella is comfort food perfection—a combination of savory meat, aromatic herbs, and molten cheese that never fails to please. It’s hearty, satisfying, and easy to make ahead, making it a go-to for family dinners or gatherings. Each slice tells a story of home-cooked warmth and creativity, blending traditional flavors with an irresistibly cheesy surprise. Whether served with potatoes, salad, or bread, this dish guarantees smiles around the table. Once you’ve tried it, it’s bound to become one of those recipes you come back to time and time again—simple, comforting, and downright delicious.